Antioxidant Inhibitors Potentiate the Cytotoxicity of Photodynamic Therapy
نویسندگان
چکیده
منابع مشابه
Antioxidant inhibitors potentiate the cytotoxicity of photodynamic therapy.
Photodynamic therapy (PDT) is an increasingly popular anticancer treatment that uses photosensitizer, light and tissue oxygen to generate cytotoxic reactive oxygen species (ROS) within illuminated cells. Acting to counteract ROS-mediated damage are various cellular antioxidant pathways. In this study, we combined PDT with specific antioxidant inhibitors to potentiate PDT cytotoxicity in MCF-7 c...
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Photodynamic therapy (PDT) uses the combination of non-toxic dyes and harmless visible light to produce reactive oxygen species that can kill cancer cells and infectious microorganisms. Due to the tendency of most photosensitizers (PS) to be poorly soluble and to form nonphotoactive aggregates, drug-delivery vehicles have become of high importance. The nanotechnology revolution has provided man...
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ژورنال
عنوان ژورنال: Photochemistry and Photobiology
سال: 2011
ISSN: 0031-8655
DOI: 10.1111/j.1751-1097.2011.01022.x